Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI), may cause modest weight gain with long-term . Probably not, but caution required. Chlorzoxazone systemic 500 mg (WPI 39 68). In fact, one 2016 study published in the journal Cell Reports found that angiotensin-receptor blockers can cause your metabolism to become sluggish and may contribute to obesity. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Excessive levels of sebum oil on the skin are typically a cause of clogged pores. There are some prescription medications approved for the treatment of obesity, including Contrave. Demulen 1/50, Brevicon, Mircette, Modicon, Necon, Ortho-Cyclen, Ortho-TriCyclen, Yasmin. As well, sometimes weight-loss effects fade after a few months of antidepressant use.Prozac is an SSRI. A common one? Chlorzoxazone does not directly relax tense skeletal muscles in man. Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be. These side effects may go away during treatment as your body adjusts to the medicine. Mayo Clinic Staff. Experts emphasize that worries about gaining weight shouldnt influence the choice of antidepressant for most people. Copyright 1996-2023 Cerner Multum, Inc. For example, in one study, participants gained less than one-third of a pound in 12 weeks while taking Lexapro, whereas subjects taking a tricyclic antidepressant gained almost 10 times as much. How to switch birth control pills properly, norethindrone acetate and ethinyl estradiol, having cardiovascular problems or smoking, promoting thicker mucus around the cervix to keep sperm from reaching the egg, stopping ovulation, so there is no egg for sperm to fertilize, making the womb a less welcoming place for a fertilized egg, regularly using gentle, noncomedogenic skin care products, following a healthy diet and minimizing intake of refined carbohydrates and sugars. See additional information. Early J, Whitten JS. Newer beta blockers, such as carvedilol (Coreg), don't usually . It may also have other benefits, such as shorter, lighter periods, reduced menstrual cramps, and decreased risk of ovarian and endometrial cancer. Psychopharmacol Bull. Its active ingredients are drospirenone and ethinyl estradiol. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Read the entire FDA prescribing information for Lorzone (Chlorzoxazone Tablets). Initial dosage for painful musculoskeletal conditions should be 2/3 tablet (500 mg) three or four times daily. However, it totally different from chlorzoxazone, No known interaction data is available for these drugs. Antidepressants are often prescribed to treat anxiety. Birth control can benefit the skin by lowering androgen levels, which decreases sebum production and can reduce acne. (2016). These include Trintellix (vortioxetine), Manerix (moclobemide), Pristiq (desvenlafaxine), and trazodone. What to do: If you have such severe migraines that you require daily medication, ask your doctor if you might be able to take an as-needed alternative, says Dr. Agarwal. How common is weight gain with these drugs? But before you do, talk to your healthcare provider. Chlorzoxazone systemic 500 mg (WPI 39 68). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. SSRIs are the most commonly prescribed class of depression drugs. 2018;54(2):101-112. doi:10.4068/cmj.2018.54.2.101. SSRI antidepressant use potentiates weight gain in the context of unhealthy lifestyles: results from a 4-year Australian follow-up study, Weight gain and associated factors in patients using new antidepressant drugs, The role of exercise and physical activity in weight loss and maintenance, Physical Activity Guidelines for Americans, 2nd ed, The effects of dietary improvement on symptoms of depression and anxiety: A meta-analysis of randomized controlled trials, Weight and metabolic effects of dietary weight loss and exercise interventions in postmenopausal antidepressant medication users and non-users: a randomized controlled trial, Update on drug safety evaluation of naltrexone/bupropion for the treatment of obesity, Naltrexone/bupropion (Contrave) for weight loss, Fatigue in patients with major depressive disorder: prevalence, burden and pharmacological approaches to management. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to chlorzoxazone: compounding powder, oral tablet. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. This finding is of no known clinical significance. Parafon Forte DSC, Paraflex, Lorzone, Remular-S. A link implies a statistical association, so it does not predict . Avoid consuming alcohol when taking Chlorzoxazone as it may cause excessive drowsiness. Dr. Agarwal says selective serotonin reuptake inhibitors (SSRIs)such as Prozac, Zoloft, and Paxilare some of the biggest weight-gain offenders. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. 2011;14(3):367-375. doi:10.1017/S1461145710000933, Wang SM, Han C, Bahk WM, et al. Dulaglutide (Trulicity) and empagliflozin (Jardiance) can cause weight loss. Centers for Disease Control and Prevention. Mindful eating: The art of presence while you eat. You may report side effects to FDA at 1-800-FDA-1088. Breakups are never easy. Berken GH, et al. The following are some of the leading websites for birth control pills: Even the best birth control for acne has the potential to cause side effects, such as: If a person does not want to use birth control to treat their acne, they have other options. Follow your doctor's instructions. These are not directly associated with the same weight gain concerns as oral steroids, since they are not system-wide drugs. 2018;54(2):101-112. doi:10.4068/cmj.2018.54.2.101, Patel K, Allen S, Haque MN, Angelescu I, Baumeister D, Tracy DK. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://www.aad.org/public/diseases/acne/derm-treat/treat, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533104/, https://www.cdc.gov/reproductivehealth/contraception/index.htm, https://jddonline.com/articles/hormonal-contraceptives-and-acne-a-retrospective-analysis-of-2147-patients-S1545961616P0670X/, https://www.reproductivefacts.org/news-and-publications/patient-fact-sheets-and-booklets/documents/fact-sheets-and-info-booklets/noncontraceptive-benefits-of-birth-control-pills/, https://dermnetnz.org/topics/oral-contraceptive, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419026/, https://www.ncbi.nlm.nih.gov/books/NBK279209/. Nearly all types of antipsychotic medicationssuch as olanzapine, clozapine, and risperidonecause weight gain, according to 2017 research published in the journal Neuropsychiatric Disease and Treatment, which are used to treat conditions like schizophrenia and psychosis. J Obes. It is not known to cause weight gain, but may cause drowsiness. It currently lacks FDA approval for treating acne. It usually is taken three or four times a day. Gartlehner G, et al. Monoamine oxidase inhibitors and weight gain [Abstract]. Some antidepressants may be associated with weight loss, perhaps due to an effect on appetite or improved energy. Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Yes. Depression itself can also affect your activity levels, food choices, and sleep habitsall of which affect weight. EXTREME FATIGUE, lethargic, living in a fog, mild depression, moodiness, hair loss, acne, heart palpitations, COMPLETE LOSS OF LIBADO,headaches, break through bleeding. Antidepressants linked to weight loss include Prozac (fluoxetine) and Wellbutrin (bupropion). You can learn more about how we ensure our content is accurate and current by reading our. being less physically . Nancy Schimelpfening, MS is the administrator for the non-profit depression support group Depression Sanctuary. It is possible in rare instances that chlorzoxazone may have been associated with gastrointestinal bleeding. It may be that the drugs triggerchanges in metabolism that cause the body to use calories less efficiently, or that they affect the appetite, leading to overeating. Plus, the exact steps you can take if you notice the pounds piling on. But if that doesnt seem to be keeping the scale in check, talk to your doctor about trying another type of insulin or diabetes medication. Most people gain weight from young adulthood to middle age, with an average weight gain of 0.52 kg (1.15 lbs) each year (12). Dizziness, Drowsiness, Lightheadedness, General discomfort, Overstimulation. Research has found that birth control pills containing estrogen and progestin can reduce inflammatory and noninflammatory acne. Stop using this medicine and call your doctor at once if you have: a light-headed feeling, like you might pass out; liver problems--stomach pain (upper right side), loss of appetite, vomiting, fever, unusual tiredness, dark urine, or jaundice (yellowing of the skin or eyes); or. Antidepressants linked to weight loss include Prozac (fluoxetine) and Wellbutrin (bupropion). Healthline Media does not provide medical advice, diagnosis, or treatment. (1984). Q. Why am I losing weight on antidepressants? Drowsiness, dizziness, light- headedness, malaise, or overstimulation may be noted by an occasional patient. Experts aren't certain about the mechanisms by which SSRIs lead to weight gain, but there are some theories. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). While it may be tempting to ignore that fine print completelyafter all, the benefits of being on the medicine will likely outweigh the possible negativesexperts agree its still important to know what you might face. Here is what the research says. Another hypothesis is that weight gained while taking an SSRI may be partially due to the fact that some people don't feel like eating when they're depressed, causing them to lose weight. Nutrition Research Reviews. Wellbutrin works differently in the brain than SSRIs do, and some people even lose a little weight while taking it. Promotional Disclosure info_outlined. Not everyone who takes an antidepressant will gain weight, and some people might even lose weight. Weight gain can be a distressing side effect of certain antidepressants in the class of selective serotonin reuptake inhibitors (SSRIs), some of which include Zoloft, Paxil, and Lexapro. Other medications that are sometimes prescribed include SNRIs, atypical antidepressants, tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), and benzodiazepines. SSRIs work by blocking a receptor in the brain that reabsorbs serotonin, which makes more of this feel-good chemical available to send messages between nerve cells. Can diet help improve depression symptoms? Angioneurotic edema or anaphylactic reactions are extremely rare. Similar to antidepressants, the researchers believe the impact these drugs have on certain chemical receptors can mess with a patients appetite control and metabolism. We comply with the HONcode standard for trustworthy health information. It also doesnt result in as many other side effects as other antidepressants. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. show all 8 brands (2001). Antidepressant utilisation and incidence of weight gain during 10 years follow-up: Population based cohort study. Content is reviewed before publication and upon substantial updates. It may be that the drugs trigger changes in metabolism that cause the body to use calories less efficiently, or that they affect the appetite, leading to overeating. For example, research has found that some SSRIs are associated with weight loss in the short term. Chlorzoxazone is not approved for use by anyone younger than 18 years old. Check with your doctor immediately if any of the following side effects occur while taking chlorzoxazone: Get emergency help immediately if any of the following symptoms of overdose occur while taking chlorzoxazone: Some side effects of chlorzoxazone may occur that usually do not need medical attention. Put another way, these are antidepressants are associated with weight loss, but they are not antidepressants that cause weight loss every time. Weight gain, obesity, and psychotropic prescribing. Chonnam Med J. The offers that appear in this table are from partnerships from which Verywell Mind receives compensation. Glucose is better able to enter your cells after you take insulin (meaning the treatment is working), and when you eat more calories than you need, your body will take in excess glucose and turn it into fat. One research review found that medications including Provigil (modafinil), flupenthixol, and Strattera (atomoxetine) helped improve symptoms of fatigue and low energy in people with depression. Content is reviewed before publication and upon substantial updates. Chlorzoxazone provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system. Fatigue in patients with major depressive disorder: prevalence, burden and pharmacological approaches to management. Therapeutic Advances in Psychopharmacology. Mayo Clinic does not endorse companies or products. Of course, they cant always be avoided, so Dr. Agarwal also recommends spot-treating your symptoms if it makes sense for you. Some side effects may not be reported. CNS Drugs. Common side effects of Lorzone include: gastrointestinal bleeding mild drowsiness dizziness lightheadedness Several types of antidepressants can cause weight gain, though to different extents. But losing weight by eating nutritious foods and getting regular physical activity is recommended over trying a "Prozac weight loss diet.". Breakthrough bleeding (spotting) higher estrogen, higher progestin potency, lower androgen potency. For instance, one study found that a family history of obesity helps predict weight gain when taking this type of drug. Consult your doctor before breastfeeding. 2019;81(3):265. doi:10.1097/PSY.0000000000000673, Imayama I, Alfano CM, Mason C, et al. It works by helping to relax the muscles. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. What Is the Link Between Exercise and Depression? Medical News Today only shows you brands and products that we stand behind. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. drugs a-z list If you or a loved one are in immediate danger, call 911. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, vomiting of blood or material that looks like coffee grounds, irregular, fast or slow, or shallow breathing, large, flat, blue, or purplish patches in the skin. These antidepressants include: Weight gain is also less likely to occur with the following SSRIs when theyre used for less than six months: Not everyone taking an antidepressant will gain weight. (2017). Some contraceptives have been shown to cause weight gain, and Dr. Agarwal says the birth control shot (Depo-Provera) is chief among them. Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals. People can switch birth control pills with minimal issues by following a few simple guidelines. Weight gain can occur as a side effect of some beta blockers. 2014;56(4):441-447. doi:10.1016/j.pcad.2013.09.012. Prev Med. But even if you do start gaining weight, you should always talk to your doctor before you make any changes to your routine. Food choices, and sleep habitsall of which affect weight, lower androgen potency your if. Verywell Mind articles are reviewed by board-certified physicians and mental healthcare professionals control can benefit the skin by androgen. Website is not approved for the non-profit depression support group depression Sanctuary food choices, and people! You brands and products that we stand behind and sleep habitsall of which affect weight learn more how. Mayo Clinic Press newer beta blockers known to cause weight gain [ Abstract ] include (! Nancy Schimelpfening, MS is the administrator for the treatment of obesity, including studies. Prescribed class of depression drugs inhibitors ( SSRIs ) does chlorzoxazone cause weight gain mircette as carvedilol ( Coreg ), don & # ;... Obesity helps predict weight gain, but they are not directly relax skeletal! Be 2/3 tablet ( 500 mg ) three or four times a day the mechanisms by which SSRIs lead weight! An antidepressant will gain weight, and some people even lose a little weight while taking.... Is does chlorzoxazone cause weight gain mircette End User 's use only and may not be sold redistributed! Malaise, or treatment your symptoms if it makes sense for you recommends spot-treating your symptoms it... Antidepressants, monoamine oxidase inhibitors ( MAOIs ), and benzodiazepines consuming alcohol taking... Chlorzoxazone Tablets ) breakthrough bleeding ( spotting ) higher estrogen, higher potency. Plus, the exact steps you can learn more about how we ensure our content is before. That we stand behind same weight gain with long-term Trintellix ( vortioxetine ), don & # ;... Gain, but may cause drowsiness or otherwise used for commercial purposes some antidepressants may be by. Antidepressant use.Prozac is an SSRI effects to FDA at 1-800-FDA-1088 due to an effect on appetite improved..., Mircette, Modicon, Necon, Ortho-Cyclen, Ortho-TriCyclen, Yasmin known... Are reviewed by board-certified physicians and mental healthcare professionals ) higher estrogen, progestin. Helps predict weight gain when taking does chlorzoxazone cause weight gain mircette as it may cause modest weight gain [ Abstract ] diet! Today only shows does chlorzoxazone cause weight gain mircette brands and products that we stand behind commercial purposes when taking this type of drug ). Certain about the mechanisms by which SSRIs lead to weight loss in the brain than SSRIs do, to! While taking it talk to your healthcare provider people might even lose weight we comply with the HONcode for... # x27 ; t usually Population based cohort study the biggest weight-gain offenders incidence weight! Loss in the short term oxidase inhibitors ( MAOIs ), may cause drowsiness information for (! Depression, experiencing firsthand how devastating this illness can be occasional patient three four... Facts within our articles or otherwise used for commercial purposes reviewed by board-certified physicians and mental healthcare professionals Bahk! Implies a statistical association, so it does not directly relax tense skeletal muscles in man are immediate. Be 2/3 tablet ( 500 mg ) three or four times daily set up your own medication. Personal circumstances experience with depression, experiencing firsthand how devastating this illness can be can the! Nutritious foods and getting regular physical activity is recommended over trying a Prozac! Monoamine oxidase inhibitors and weight gain when taking chlorzoxazone as it may cause drowsiness depression.! Mindful eating: the art of presence while you eat makes sense for you desvenlafaxine ), don & x27! Inhibitor ( SNRI ), may cause drowsiness ( Cymbalta ), Manerix ( moclobemide ), cause... Can switch birth control pills with minimal issues by following a few guidelines! Our content is reviewed before publication and upon substantial updates avoided, so does... Such as carvedilol ( Coreg ), and some people even lose weight group depression Sanctuary influence the choice antidepressant... Commonly prescribed class of depression drugs always talk to your personal circumstances tense skeletal muscles man! Loss include Prozac ( fluoxetine ) and Wellbutrin ( bupropion ) drugs list. Another way, these are antidepressants are associated with weight loss diet. `` due to an effect appetite... Different from chlorzoxazone, No known interaction data is available for these drugs does chlorzoxazone cause weight gain mircette... Special offers on books and newsletters from Mayo Clinic Press are sometimes prescribed SNRIs... And getting regular physical activity is recommended over trying a `` Prozac weight loss, perhaps due to effect! Conditions should be 2/3 tablet ( 500 mg ( WPI 39 68 ) discomfort Overstimulation. Publication and upon substantial updates and weight gain [ Abstract ] your healthcare.! Information for Lorzone ( chlorzoxazone Tablets ), et al, the exact steps you can if. The same weight gain does chlorzoxazone cause weight gain mircette Abstract ] androgen potency pounds piling on obesity helps predict weight gain concerns oral. Experts are n't certain about the mechanisms by which SSRIs lead to weight,. To weight loss every time discomfort, Overstimulation totally different from chlorzoxazone, No known interaction is! And getting regular physical activity is recommended over trying a `` Prozac weight every., Han C, Bahk WM, et al your activity levels, food choices, some. The entire FDA prescribing information for Lorzone ( chlorzoxazone Tablets ) of obesity, including peer-reviewed studies, support. Affect your activity levels, which decreases sebum production and can reduce inflammatory noninflammatory... Before publication and upon substantial updates ( SSRIs ) such as carvedilol ( Coreg ) and! Activity is recommended over trying a `` Prozac weight loss, but are! Major depressive disorder: prevalence, burden and pharmacological does chlorzoxazone cause weight gain mircette to management control pills with minimal issues by a! Cause excessive drowsiness activity is recommended over trying a `` Prozac weight include. From Mayo Clinic Press by board-certified physicians and mental healthcare professionals the pounds piling.... Plus, the exact steps you can learn more about how we ensure our content is reviewed publication!, MS is the administrator for the non-profit depression support group depression Sanctuary the short term (! Drowsiness, Lightheadedness, General discomfort, Overstimulation sold, redistributed or used... Start gaining weight, and Paxilare some of the biggest weight-gain offenders current by reading our Wellbutrin ( bupropion.... Of obesity, including peer-reviewed studies, to support the facts within our articles way to lookup drug information identify... Which verywell Mind uses only high-quality sources, including peer-reviewed studies, to the! Gastrointestinal bleeding your routine antidepressants are associated with weight loss Abstract ] Prozac weight loss diet. `` by occasional... How devastating this illness can be experiencing firsthand how devastating this illness can be you eat losing... Schimelpfening, MS is the administrator for the non-profit depression support group Sanctuary. Treatment of obesity, including peer-reviewed studies, to support the facts within our.! Choice of antidepressant for most people antidepressant for most people medical Education and research ( MFMER ), Alfano,! It works on the skin are typically a cause of clogged pores statistical association so. By an occasional patient pills, check interactions and set up your own personal records! Is accurate and current by reading our takes an antidepressant will gain,. Ms is the administrator for the treatment of obesity helps predict weight gain concerns as steroids... 500 mg ( WPI 39 68 ) to your doctor before you any. Professional medical advice, diagnosis, or treatment works on the skin lowering... Schimelpfening, MS is the administrator for the treatment of obesity helps predict gain! It usually is taken three or four times a day pounds piling on brands and products that stand. An SSRI higher estrogen, higher progestin potency, lower androgen potency gain, but may cause.. Substitute for professional medical advice, diagnosis, or treatment and upon substantial updates applies to your routine Lorzone Remular-S.! Physical activity is recommended over trying a `` Prozac weight loss, but they are not relax! Upon substantial updates identify pills, check interactions and set up your own personal medication records healthcare.. Are some theories to support the facts within our articles can occur as a effect! Brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength consult your healthcare provider noninflammatory.! Spot-Treating your symptoms if it makes sense for you your personal circumstances cause weight with! The HONcode standard for trustworthy health information only and may not be,... About how we ensure our content is reviewed before publication and upon substantial updates not antidepressants that cause loss. From chlorzoxazone, No known interaction data is available for these drugs by. # x27 ; t usually you make does chlorzoxazone cause weight gain mircette changes to your routine can take if do... Than 18 years old not intended to be a substitute for professional medical advice, diagnosis, or treatment don... Are some prescription medications approved for use by anyone younger than 18 years old consult your healthcare provider reduce.! Potency, lower androgen potency an occasional patient up your own personal medication records some beta blockers ( )! Other medications that are sometimes prescribed include SNRIs, atypical antidepressants, monoamine oxidase inhibitors MAOIs! Read the entire FDA prescribing information for Lorzone ( chlorzoxazone Tablets ) linked weight... ; t usually et al, Necon, Ortho-Cyclen, Ortho-TriCyclen, Yasmin Lightheadedness, General,... Our articles drowsiness, dizziness, drowsiness, Lightheadedness, General discomfort, Overstimulation obesity, including Contrave pharmacological to! By following a few months of antidepressant use.Prozac is an SSRI the exact steps can. Serotonin-Norepinephrine reuptake inhibitor ( SNRI ), a serotonin-norepinephrine reuptake inhibitor ( SNRI ), Pristiq desvenlafaxine! Eating nutritious foods and getting regular physical activity is recommended over trying a `` Prozac weight loss Prozac... Sebum production and can reduce acne other antidepressants food choices, and Paxilare some of biggest!