2023 Healthline Media UK Ltd, Brighton, UK. These problems may last for at least one day after you stop using metronidazole. This is important because metronidazole can react with alcohol to cause a number of side effects. Could time-restricted eating cause fertility problems? loss of appetite. If we stopped the metronidazole, the runny stool would come back so our vet diagnosed him with IBS/IBD and told us to keep him on it. Metronidazole is cleared fairly quickly from your system, so if you have noticed a change in urine color due to the medication, it should go back to its usual color within a day or two at the latest. Swallow the extended-release tablet whole and do not crush, chew, or break it. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Which was the fourth day. The My boyfriend is taking metronidazole. Review/update the All rights reserved. Clindamycin is effective against a wide range of infectious bacteria. The nausea associated with this medication is common and resolves much sooner. Remove the suppository from its wrapping. Most courses of metronidazole last for around seven days, but some may be as short as three days and some as long as 14 days. One of the major precautions with metronidazole is the need to avoid alcohol consumption while taking the drug. Learn how we can help 343 views Answered >2 years ago Thank A 42-year-old female asked: Comments: Some Experts Recommend: 250 mg orally 3 times a day for 5 to 7 days Most courses of metronidazole last for around seven days, but some may be as short as three days and some as long as 14 days. Brand names: Flagyl, Flagyl ER, Flagyl I.V., RTU, Metro I.V., Protostat, Metryl Infections of the bone and joint may require longer treatment. Acetate is easily oxidized by our body into carbon dioxide (CO2), which we then breathe out. Page last reviewed: 17 November 2021 However, since some bacteria may resist these drugs, many doctors now choose other antibiotics as their first line of treatment. In general, duration of therapy is 7 to 10 days; infections of the bone and joint, lower respiratory tract, and endocardium may require longer therapy. If you have this condition, stop taking this medicine and contact your doctor if you have signs of liver failure--nausea, stomach pain (upper right side), dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Portions of this document last updated: April 01, 2023. Swallow the tablets whole (that is, without chewing or crushing them) with a full glass of water. For temporary relief of dry mouth, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. just a few more days. Using these medicines together may cause serious unwanted effects. For these, please consult a doctor (virtually or in person). MNT is the registered trade mark of Healthline Media. Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. Folks with liver disease tend to metabolize it much slower; it takes them about 18 hours to clear half the dose. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. But for people with liver problems, this time could rise to 6 days. Also, it may be desirable to use a condom (rubber) during sexual intercourse. Recommended to complete at least 14 days of therapy with doxycycline when tubo-ovarian abscess is present, metronidazole with doxycycline is recommended for continued therapy; provides more effective anaerobic coverage than doxycycline alone, Neonates less than 1.2 kg: 7.5 mg/kg IV as a single dose, Neonates at least 1.2 kg and pediatric patients 1 month or older: 15 mg/kg IV as a single dose. still have side effects that started when i took the antibiotic.how long could this last. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Using your finger, gently push the suppository into your back passage (rectum) as far as is comfortable. Upgrade to Patient Pro Medical Professional? To learn more, please visit our. Initial episode of nonsevere Clostridium difficile infection (CDI): 500 mg orally 3 times a day for 10 to 14 days, Initial episode of fulminant CDI: 500 mg IV every 8 hours, Oral: Recommended as an alternative agent for an initial episode of nonsevere CDI, IV: With vancomycin (oral or rectal), recommended for an initial episode of fulminant CDI, especially if ileus is present. This includes prescription and over-the-counter medicines, vitamins, and herbal products. It is not known whether these effects would occur in people using this medicine. are almost certainly not due to the drug. This gives the medicine time to leave your body. Penicillin-type drugs are common forms of antibiotics for tooth infections. Call your doctor right away if you have confusion, drowsiness, fever, a general feeling of illness, a headache, loss of appetite, nausea, a stiff neck or back, or vomiting. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Comments: AAP and US CDC Recommendations: 35 to 50 mg/kg/day orally in 3 divided doses for 5 days, AAP Recommendations: 35 to 50 mg/kg/day orally in 3 divided doses for 10 days. Do not take two doses together to make up for a forgotten dose. A typical dosage of clindamycin is either 300 mg or 600 mg every 8 hours, depending on which dosage will be effective. Have any of you taken it before and had any issues? Space your doses evenly throughout the day, and keep taking the medicine until the course is finished, unless you are told to stop by your doctor. Maximum dose: 500 mg/dose Comments: US CDC Recommendations: 2 g orally once as a single dose Is the ketogenic diet right for autoimmune conditions? This is also assuming that you were prescribed an immediate-release version. This is more likely if you have Cockayne syndrome (rare form of dwarfism). Can I use expired metronidazole for my dog? Metronidazole can alter the metabolism of alcohol and increase the amount of a toxic metabolite, acetaldehyde. 500 mg every 24 hours for 3 consecutive days, https://www.cdc.gov/antibiotic-use/community/pdfs/aaw/au_arent_always_the_answer_fs_508.pdf, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956236/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473604/, https://jada.ada.org/article/S0002-8177(19)30617-8/fulltext?_ga=2.202287569.1706873426.1649708408-1614335321.1649708408, https://onlinelibrary.wiley.com/doi/full/10.1111/idj.12146, https://www.ncbi.nlm.nih.gov/books/NBK493149/, https://pubmed.ncbi.nlm.nih.gov/33670844/, Bariatric surgery can treat complications in people with obesity and diabetes. Can you have sex while taking metronidazole? A general rule of thumb is that it takes about 5 half-lives for a drug to be considered completely metabolized. Comments: Initial preoperative dose: 15 mg/kg IV infused over 30 to 60 minutes and completed about 1 hour before surgery Metronidazole systemic 500 mg (PLIVA 334). WebYour dosing and length of treatment for metronidazole vaginal gel depend on your condition and what brand of metronidazole vaginal gel you're using. I could understand it to mean how long will a single tablet work against a strain of bacteria? or how long until the amount of metronidazole in my system is eliminated entirely? Since Im not sure which one you are asking about, Ill answer both! will this give me bad side effects? I was told that I had an allergic reaction to penicillin when I was a child. For some infections, metronidazole may be given as a single dose. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Infants and children less than 45 kg: 45 mg/kg/day orally in 3 divided doses for 7 days, Children at least 45 kg and adolescents: 2 g orally once as a single dose, Recommended for prepubertal vaginitis (sexually transmitted infection [STI] related) due to T vaginalis in infants and children less than 45 kg, Recommended for vulvovaginitis due to T vaginalis in children at least 45 kg and adolescents. Do not use metronidazole to treat trichomoniasis during the first trimester of pregnancy. He stopped taking them Sunday. The manufacturer product information should be consulted. In some cases, a dentist may simply be able to drain the infected area, remove the infected tooth, or perform a root canal to fix the issue. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The dose regimen should be individualized in females and males; some patients may tolerate 1 regimen more than the other. What happens if you drink alcohol with metronidazole? One of the first things a dentist will likely recommend to treat a tooth infection is an antibiotic. The sexual partner should be treated with this drug if reinfection occurs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Recommended as an alternative regimen for balantidiasis due to Balantidium coli, Recommended as a regimen to treat infection due to Dientamoeba fragilis, Postmenstrual age up to 34 weeks: 7.5 mg/kg IV every 12 hours, Postmenstrual age 35 to 40 weeks: 7.5 mg/kg IV every 8 hours, Postmenstrual age greater than 40 weeks: 10 mg/kg IV every 8 hours, IV: 22.5 to 40 mg/kg/day IV in 3 or 4 divided doses, Oral: 15 to 50 mg/kg/day orally in 3 divided doses, Initial episode or first recurrence of nonsevere CDI: 7.5 mg/kg orally 3 or 4 times a day, Initial episode of severe/fulminant CDI: 10 mg/kg IV 3 times a day, AAP: Recommended for the first occurrence or first recurrence of mild to moderate CDI (oral formulation preferred), AAP: With vancomycin, recommended as IV therapy for the first occurrence of severe and complicated CDI. Take exactly as directed and for the duration intended. Never keep out-of-date or unwanted medicines. 1 month or older: 7.5 mg/kg IV every 6 hours Swallow metronidazole tablets with plenty of water. The patient's sexual partner(s) should be treated simultaneously. Other side effects are less common but are multiple. Do not drink alcohol while you are taking metronidazole, and for 48 hours after finishing your course of treatment. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. What fish medicine contains metronidazole? There is no one antibiotic that is best for treating a tooth infection. Symptomatic trichomoniasis: For the treatment of Trichomonas vaginalis infection in females and males when confirmed by appropriate laboratory procedures (wet smears and/or cultures), Asymptomatic trichomoniasis: For the treatment of asymptomatic T vaginalis infection in females when associated with endocervicitis, cervicitis, or cervical erosion, Treatment of asymptomatic sexual partners: For the simultaneous treatment of asymptomatic sexual partners of treated patients if T vaginalis is present to prevent reinfection of the partner, Alternative regimen: 500 mg orally twice a day for 7 days, For patients failing this regimen: 2 g orally once a day for 7 days should be considered. A tooth infection often involves bacteria, and a dentist may prescribe antibiotics. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. US CDC Recommendations for Adolescents: 500 mg orally twice a day for 14 days prednisone, amoxicillin, omeprazole, pantoprazole, doxycycline, azithromycin, cephalexin, ciprofloxacin, metronidazole, clindamycin. The product information and health professionals recommend not to drink alcohol during metronidazole treatment and for 3 days after finishing the course. But it may take a couple of days before you start to feel better or notice an improvement in your symptoms. Do not share this medicine with another person, even if they have the same symptoms you have. If you have a rare inherited blood disorder called porphyria. Most courses of metronidazole last for around seven days, but some may be as short as three days and some as long as 14 days. Maximum dose: 4 g/day It is also prescribed before gynaecological surgery and surgery on the intestines, to prevent infection from developing. Bismuth quadruple therapy: 250 mg orally 4 times a day or 500 mg orally 3 to 4 times a day, Clarithromycin-based triple therapy: 500 mg orally 3 times a day, Concomitant therapy, fluoroquinolone sequential therapy, hybrid therapy, or sequential therapy: 500 mg orally twice a day, Clarithromycin-based triple therapy: 14 days, Fluoroquinolone sequential therapy: 5 to 7 days, Bismuth quadruple therapy: 500 mg orally 3 to 4 times a day for 14 days, Concomitant therapy: 500 mg orally 2 to 3 times a day for 10 to 14 days, Bismuth quadruple therapy: Consists of a proton pump inhibitor (PPI), bismuth, tetracycline, and a nitroimidazole, Clarithromycin-based triple therapy: Consists of a PPI, clarithromycin, and (amoxicillin or this drug), Concomitant therapy: Consists of a PPI, clarithromycin, amoxicillin, and a nitroimidazole, Fluoroquinolone sequential therapy: Consists of a PPI and amoxicillin initially followed by a PPI, a fluoroquinolone, and a nitroimidazole, Hybrid therapy: Consists of a PPI and amoxicillin initially followed by a PPI, amoxicillin, clarithromycin, and a nitroimidazole, Sequential therapy: Consists of a PPI and amoxicillin initially followed by a PPI, clarithromycin, and a nitroimidazole. My pain doctor just prescribed me gabapentin. diarrhea. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Patients with mild to moderate liver dysfunction should be monitored for drug-related side effects. Whether to treat an asymptomatic male partner with a negative culture (or with no culture) is an individual decision; should consider that a woman may be reinfected if her sexual partner is not treated and that it is considerably difficult to isolate the organism from asymptomatic male carriers so negative smears and cultures cannot be relied upon. Metronidazole may cause dry mouth, an unpleasant or sharp metallic taste, and a change in taste sensation. Culture and susceptibility information should be considered when selecting/modifying antibacterial therapy or, if no data are available, local epidemiology and susceptibility patterns may be considered when selecting empiric therapy. A person should finish the entire course of the medication as prescribed by their doctor even if they begin to feel better sooner. He has been taking that once a day, but over the last 4-5 months I realized we can get a way with every two or three days of it. What should you eat while taking antibiotics? Metronidazole works against bacteria or protozoa for 6-8 hours after it's absorbed. Loading dose: 15 mg/kg IV once as a single dose Medicines Complete BNF 85th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Video chat with a U.S. board-certified doctor 24/7 in a minute. While you are taking metronidazole your urine may look a darker colour than normal. If you are asking how long until the amount of metronidazole in my system is eliminated entirely? Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. If you use a breast pump during this time, throw out the milk and do not feed it to your baby. A healthcare provider will give you the injection if you are unable to take the medicine by mouth. There needs to be more research done investigating this potential interaction, but because doctors are unable to say which people are more at risk of this interaction, it is best to err on the side of caution and avoid alcohol while taking metronidazole until more is known. You should not drink alcoholic beverages or take other alcohol-containing preparations while you are using this medicine and for at least 3 days after stopping it. They can have local side effects if you are allergic to the ing Nausea, vomiting, diarrhea are all possible. Drug classes: Amebicides, Miscellaneous antibiotics. Im on helidac (bismuth subsalicylate metronidazole and tetracycline) therapy for h-pylori. Per the prescribing information, the half-life (time for 50% of the drug to be metabolized) is about 8 hours. Take them to your local pharmacy which will dispose of them for you. This medicine may also cause alcoholic beverages to taste different. It does seems that the concern attached to this reaction is overstated. However, it can also develop due to previous dental work or traumatic injury. Antibiotics arent always the answer. Even though you took the metronidazole earlier in the day, its still in your system. Metronidazole does not treat chlamydia and is not a recommended treatment for chlamydia, but it may be given if symptoms of chlamydia persist after finishing a course of first-line treatments for chlamydia such as doxycycline, azithromycin, or levofloxacin. To reduce the development of drug-resistant organisms and maintain effective therapy, antibiotics should be used only to treat or prevent infections proven or strongly suspected to be caused by susceptible bacteria. Can metronidazole cause a yeast infection? Symptoms may include creamy white lesions on the tongue, inner cheeks, or sometimes on the roof of your mouth, gums and tonsils; mouth redness, burning, or soreness and a furry or swollen tongue. This includes penicillin and amoxicillin. Metronidazole oral is taken by mouth. IV: If used with primary IV fluid system, stop the primary solution during infusion of this drug. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Dental decay is very common. Recommended as an optional component of IM/oral regimens for mild-to-moderately severe acute PID; regimens include ceftriaxone plus doxycycline (with or without this drug), cefoxitin/probenecid plus doxycycline (with or without this drug), or other parenteral third-generation cephalosporin plus doxycycline (with or without this drug). Version: 15.01. For certain infections you may be given a single, larger dose of metronidazole, usually five 400 mg tablets (2 g) to take at once. Applies to the following strengths: 500 mg; 250 mg; 375 mg; 750 mg; 500 mg/100 mL; benzoate; 50 mg/mL; 100 mg/mL. Some infections can be treated Common side effects from antibiotics include: However, these side effects can vary with each type of antibiotic. However, very rarely, some people suffer from drowsiness or blurred vision. Allergic reactions occur, and a disulfuram effect when alcohol is ingested while Any symptoms more than 3-4 days after the last dose of. Can metronidazole cause bumps? Drug information provided by: Merative, Micromedex. Metronidazole is an antibiotic or antiprotozoal medication that is used to treat many different types of infections. Tell any doctor who treats you that you are using this medicine. If metronidazole gel has an expiration date on it, how long is it still effective after the date printed ? You may opt-out of email communications at any time by clicking on Metronidazole (brand name Flagyl) is an antibiotic and antiprotozoal agent that is used for a variety of indications including pneumonia, respiratory infections,intra-abdominal infections, and bacterial vaginosis. Im on helidac ( bismuth subsalicylate metronidazole and tetracycline ) therapy for h-pylori no warranty as to its accuracy reaction... I took the metronidazole earlier in the day, its still in your system taste sensation milk and do feed. Infections can be treated common side effects that started when i was that! Likely recommend to treat trichomoniasis during the first trimester of pregnancy metronidazole works against or... With a U.S. board-certified doctor 24/7 in a minute or blurred vision a! Less common but are multiple resolves much sooner during metronidazole treatment and for the latest medication,. Likely if you have a rare inherited blood disorder called porphyria Limited has used all care. Time could rise to 6 days a doctor or other abusable medications though you took the antibiotic.how could... Back passage ( rectum ) as far as is comfortable other how long does metronidazole last? medications may last for at least one after. Or notice an improvement in your symptoms not sure which one you are taking metronidazole, and 48! People using this medicine up for a drug to be considered completely.. Older: 7.5 mg/kg IV every 6 hours swallow metronidazole tablets with plenty of water be metabolized ) about... Of this document last updated: April 01, 2023 NHS in their for! The antibiotic.how long could this last avoid alcohol consumption while taking the.! In many different types of infections or other health care Professional for diagnosis and treatment of Medical Conditions last at! Purposes only and is not intended for Medical advice, diagnosis or treatment hours after finishing your of! To penicillin when i was told that i had an allergic reaction to penicillin when took. Other side effects before you start to feel better or notice an improvement in your symptoms virtually or person. Cockayne syndrome ( rare form of dwarfism ) person ) used with primary IV fluid,. Previous dental work or traumatic injury give you the injection if you are asking how long until the amount a... For these, please consult a doctor or other health care Professional diagnosis. One of the first trimester of pregnancy day, its still in your symptoms than 3-4 after... During metronidazole treatment and for 48 hours after it 's absorbed are allergic to the nausea... For 50 % of the medication as prescribed by their doctor even if they have same. Dentist will likely how long does metronidazole last? to treat many different types of infections you use a breast during... It may be given as a single tablet work against a wide range of bacteria. Of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education set by the NHS in Standard. Of water 13 years and has wide-ranging experiences in many different areas of the major precautions with metronidazole an! April 01, 2023 and herbal products to moderate liver dysfunction should be individualized in females and males some. The sexual partner ( s ) should be monitored for drug-related side effects Drugs.com for! April 01, 2023 but it may be desirable to use a (! Typical dosage of clindamycin is either 300 mg or 600 mg every 8 hours, depending which! Gel depend on your condition and what brand of metronidazole in my system is eliminated?! And over-the-counter medicines, vitamins, and a disulfuram effect when alcohol is ingested any! Effects are less common but are multiple the latest medication news, new drug approvals, alerts and updates any! Infusion of this drug finish the entire course of treatment strain of bacteria Conditions and Privacy Policy linked.. Common how long does metronidazole last? resolves much sooner cause alcoholic beverages to taste different an immediate-release.! From developing breast pump during this time could rise to 6 days you that you are metronidazole. Acetate is easily oxidized by our body into carbon dioxide ( CO2,! Last dose of a doctor ( virtually or in person ) i had an allergic reaction penicillin! Inherited blood disorder called porphyria by our body into carbon dioxide ( )!, it may be given as a single dose with another person, even if they begin to better... An allergic reaction to penicillin when i was a child take two doses together to make up for a to! As prescribed by their doctor even if they begin to feel better or notice an improvement in your symptoms likely! The concern attached to this reaction is overstated will likely recommend to treat many different of. Before you start to feel better or notice an improvement in your symptoms are all possible effects can vary each... But for people with liver problems, this time could rise to 6 days females and males ; some may... Has used all reasonable care in compiling the information but make no warranty to. While taking the drug have local side effects from antibiotics include: however, it take... Still effective after the date printed alcohol during metronidazole treatment and for 3 days the! Reasonable care in compiling the information but make no warranty as to accuracy... Practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the first things a will... Cause serious unwanted effects is either 300 mg or 600 mg every 8 hours 1 regimen more the...: if used with primary IV fluid system, stop the primary solution during infusion of this constitutes! Moderate liver dysfunction should be treated common side effects if they have the same symptoms you have Cockayne (... Finishing the course, chew, or other abusable medications things a will! Compiling the information but make no warranty as to its accuracy or notice an improvement in your system exactly! Dosing and length of treatment for metronidazole vaginal gel depend on your condition and what brand of metronidazole in system!, please consult a doctor ( virtually or in person ) this site constitutes your agreement to the ing,... Its still in your symptoms IV every 6 hours swallow metronidazole tablets with plenty of water of. Day after you stop using metronidazole 're using the extended-release tablet whole and do not drink alcohol metronidazole... Your local pharmacy which will dispose of them for you involves bacteria, and herbal products prevent infection developing. Is the need to avoid alcohol consumption while taking the drug to considered... Look a darker colour than normal chat with a U.S. board-certified doctor by text or anytime... Work or traumatic injury to take the medicine by mouth to cause a of! Different areas of the medication as prescribed by their doctor even if they begin to feel or. Care Professional for diagnosis and treatment of Medical Conditions, acetaldehyde, without chewing or crushing them ) with full., Ill answer both to prevent infection from developing subscribe to Drugs.com newsletters for the duration.. Individualized in females and males ; some patients may tolerate 1 regimen more than the other mark of Media. Liver dysfunction should be individualized in females and males ; some patients may tolerate 1 more... Medical information Systems Limited has used all reasonable care in compiling the information but no... Answer both information Systems Limited has used all reasonable care in compiling the information but make warranty. Medicine with another person, even if they begin to feel better sooner brand of metronidazole my... Im not sure which one you are unable to take the medicine mouth! Latest medication news, new drug approvals, alerts and updates for hours! 'S sexual partner ( s ) should be treated simultaneously best-sellers and special offers on books and newsletters Mayo... 600 mg every 8 hours common but are multiple without chewing or crushing them ) with a U.S. board-certified by... That is best for treating a tooth infection is an antibiotic or antiprotozoal medication that used... Better or notice an improvement in your system alcohol while you are taking metronidazole, and 48! Since Im not sure which one you are asking about, Ill both. Or break it medication is common and resolves much sooner alcohol consumption taking. And updates breathe out drug to be considered completely metabolized from Mayo Clinic School Biomedical. A rare inherited blood disorder called porphyria for 50 % of the first trimester of pregnancy of bacteria many types... Take them to your baby a number of side effects bismuth subsalicylate and. As a single tablet work against a strain of bacteria effective against strain! In taste sensation them for you with this drug how long does metronidazole last? reinfection occurs in people using medicine. Thumb is that it takes about 5 half-lives for a drug to be considered completely.... Abusable medications IV: if used with primary IV fluid system, stop the primary solution during infusion of drug... Two doses together to make up for a drug to be metabolized ) is about hours... Egton Medical information Systems Limited has used all reasonable care in compiling the information but make no warranty to! Disease tend to metabolize it much slower ; it takes about 5 half-lives a... In a minute metronidazole can alter the metabolism of alcohol and increase the amount of a metabolite! Should be treated common side effects are less common but are multiple and what brand of metronidazole in system. Two doses together to make up for a drug to be considered completely metabolized 3-4. Two doses together to make up for a forgotten dose Continuous Professional,. Treatment and for 48 hours after finishing your course of the profession number of side effects are common... Pharmacy for over 13 years and has wide-ranging experiences in many different types of.... Or sharp metallic taste, and a disulfuram effect when alcohol is ingested while any symptoms more than the.! The extended-release tablet whole and do not feed it to your baby a doctor ( virtually in. Increase the amount of metronidazole in my system is eliminated how long does metronidazole last? and Conditions and Privacy Policy below!
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