You can use the study as a second opinion to make health care decisions. They may also recommend changes to your Topamax or metformin treatment to avoid the interaction happening again. Examples include Stevens-Johnson syndrome and toxic epidermal necrolysis. Gabapentin can help control seizures as well as nerve pain from shingles. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. However, this effect tends to be mild . Medication Guide: Topamax. Allergic reaction. Drug interactions with topiramate oral and loratadine oral, Significant interaction possible (monitoring by your doctor required). You should avoid drinking alcohol while taking Topamax. Any hair you lose while taking Topamax is expected to grow back after you stop taking the drug. Dehydration can raise your risk of metabolic acidosis. Taking Topamax with metformin could increase the level of metformin in your blood. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. After you stop taking Topamax, the symptoms you were taking it for may return. Sharing this information with them may help prevent possible interactions. 2016;165:409. Clinical features of bipolar spectrum with binge eating behaviour. Does Topamax cause long-term side effects or permanent side effects? In: Diagnostic and Statistical Manual of Mental Disorders DSM-5. National Alliance on Mental Illness. If you have problems with bleeding, your doctor may recommend switching either your Topamax or SSRI treatment. Examples include: If you have more questions about your risk of certain side effects from Topamax, talk with your doctor or pharmacist. If youve had an allergic reaction to Topamax or any of its ingredients, your doctor will likely not prescribe Topamax. Following a ketogenic diet while taking Topamax can increase your risk of metabolic acidosis (a high level of acid in your bodily fluids). If you have trouble understanding this information, your doctor or pharmacist can help. They can discuss with you whether its safe to do so while taking Topamax. Topamax can cause certain stomach-related side effects. Typically, treating binge-eating disorder on your own isn't effective. loratadine oral brand names and other generic formulations include: Alavert Children's Allergy Oral, Alavert Oral, Allerclear Oral, Allergy Relief (loratadine) Oral, Children's Allergy Relief (loratadine) Oral, Children's Claritin Oral, Claritin Liqui-Gel Oral, Claritin Oral, Claritin RediTabs Oral, Loradamed Oral, Non-Drowsy Allergy Oral, Tavist ND Oral, Vicks QlearQuil Allergy Oral, Wal-itin Aller-Melts Oral, Wal-itin Oral, Wal-vert Oral. They may recommend switching to a different antidepressant or migraine treatment to avoid the interaction. If this side effect goes untreated, it can lead to weakening of the bones. topiramate oral brand names and other generic formulations include: Qudexy XR Oral, Topamax Oral, Topiragen Oral, Trokendi XR Oral. Otherwise, call a poison control center right away. topiramate oral will decrease the level or effect of loratadine oral by altering drug metabolism. What are the mild side effects of Topamax? Or call 888-233-2334. The information provided here is for informational purposes only. But this side effect wasnt reported in studies. Neuropsychiatr Dis Treat. Note that the information below does not include all other possible interactions with Topamax. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Your doctor may monitor your acid levels more closely than usual during treatment. a type of seizure disorder called tonic-clonic epilepsy. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication. 2012 Jun;52(6):930-45. doi: 10.1111/j.1526-4610.2012.02185.x, Silberstein SD, Neto W, Schmitt J, Jacobs D & MIGR-001 Study Group. Tell your doctor right away if you experience sudden/unexplained tiredness, vomiting, or mental changes (such as decreased alertness). If your doctor confirms you had a serious allergic reaction to Topamax, they may have you switch to a different treatment. A stimulant, Vyvanse can be habit-forming and abused. Medication Guide: Topamax. If you have epilepsy or migraine, your doctor may suggest Topamax. Know someone with epilepsy? All rights reserved. Here's how to tell them, Stressed? Before starting treatment, talk with your doctor and pharmacist. Keep in mind that this chart does not include all drugs that may interact with Topamax. Letrozole Interactions. Your medical care provider also may want you to have other tests to check for health consequences of binge-eating disorder, such as high cholesterol, high blood pressure, heart problems, diabetes, GERD and some sleep-related breathing disorders. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Are there any side effects of Topamax that I should tell you about right away? If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately talk to your doctor about the benefits and risks of using this medication during pregnancy. Tell your doctor right away if you have any serious side effects, including: signs of kidney stones (such as severe back/side/abdominal/groin pain, fever, chills, painful/frequent urination, bloody/pink urine), rapid breathing, fast/slow/irregular heartbeat, bone pain, broken bones, loss of consciousness, unusual bleeding/bruising. Following this type of diet can help reduce seizures in some people with epilepsy. Merck Manual Professional Version. Properly discard this product when it is expired or no longer needed. This medication may make you sweat less, making you more likely to get heat stroke. Topamax (topiramate) is a prescription drug thats used to treat epilepsy and help prevent migraine headaches. Clinical Drug Interactions Source: Medscape from WebMD. Bipolar disorder with comorbid binge eating history: A genome-wide association study implicates APOB. But in addition to professional help, you can take these self-care steps to reinforce your treatment plan: Most dietary supplements and herbal products designed to suppress the appetite or aid in weight loss are ineffective and may be misused by people with eating disorders. Its characterized by seizures that develop in the presence of musical triggers. If you are experiencing serious medical symptoms, seek emergency treatment immediately. chronic obstructive pulmonary disease (COPD), Common questions about Topamax and interactions, Dosage for Topamax: What You Need to Know, Side Effects of Topamax: What You Need to Know, sites.psu.edu/cannabinoid/files/2020/06/Cannabinoid-as-PRECIPITANT-Medication-Affecting-the-Metabolism-of-ANOTHER-OBJECT-Medication_04_25.pdf, sites.psu.edu/cannabinoid/files/2020/06/NTI-Meds-to-be-Closely-Monitored-when-Co-Administered-with-Cannabinoids_2020_04_25.pdf, accessdata.fda.gov/drugsatfda_docs/label/2022/020505s062,020844s053lbl.pdf, pdr.net/drug-summary/Topamax-topiramate-947, Topamax and Depression: What You Need to Know, 9 Preventive Therapies (Prophylaxis) for Migraine, Seizure Types and Symptoms, and How to Administer Emergency Aid, levonorgestrel/ethinyl estradiol (Seasonique), can make birth control less effective than usual, can make other seizure medication less effective than usual, can increase the risk of side effects from Topamax and CNS depressants, can increase the risk of side effects from amphetamines, can increase the risk of side effects from Topamax and anticholinergics, can increase the risk of seizures in people with, can increase the risk of side effects from Topamax and SSRIs, can increase the risk of side effects from Topamax and SNRIs, can increase the risk of side effects from Topamax and NSAIDs, can increase the risk of side effects from Topamax and blood thinners, can increase the risk of side effects from Topamax and metformin, can increase the risk of side effects from Topamax, can increase the risk of seizures in people with epilepsy, and can increase the risk of side effects from bupropion and Topamax, can increase the risk of side effects from lithium, can increase the risk of side effects from Topamax and divalproex, Not in the United States? And natural doesn't always mean safe. The phase IV clinical study analyzes what interactions people who take Topamax and Trazodone hydrochloride have. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. Eating Behaviors. There are 103 drugs known to interact with letrozole, along with 3 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 3 are major, 93 are moderate, and 7 are minor. I take topamax 100 mg, Zyrtec 10 mg,Trileptal 600mg, plus Benedryl everynight and I am still alive. To diagnose binge-eating disorder, your medical care provider may recommend a psychological evaluation, including discussion of your eating habits. Another problem in the bladder caused rarely by Topamax is the frequent need to urinate. Last medically reviewed on October 7, 2022. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking topiramate and each time you get a refill. More common side effects in people taking Topamax for migraine include: More common side effects in people taking Topamax for epilepsy include: Read on to learn about other mild and severe side effects that can happen with Topamax. What does your typical daily food intake look like? All rights reserved. Should I avoid certain foods while taking Topamax? The list below includes factors to consider. If you have any eye problems while taking Topamax, tell your doctor right away. Effexor, Pristiq, Edronax, Lexapro, and Remeron. Consult your doctor or pharmacist for more details. Urinary incontinence or the loss of the ability to control the function of the bladder is a possible but rare side effect of topiramate usage 1. Here are some tips to help you cope: If you have binge-eating disorder, you and your family may find support groups helpful for encouragement, hope and advice on coping. Take this medication by mouth with or without food as directed by your doctor, usually twice daily. This is not insurance. This could worsen conditions such as osteoporosis, osteomalacia, and rickets. When sought illegitimately, it is usually requested as a psychiatric drug or headache medication. Accessed Jan. 31, 2018. 2010;6:17-28. doi:10.2147/ndt.s6459, Silberstein SD. Discuss the use of reliable forms of birth control with your doctor (see also Drug Interactions section). This medication belongs to a class of drugs known as anticholinergics/antispasmodics. (Withdrawal symptoms are side effects that can happen when you stop taking a drug.). CNS Spectrum. If you use dietary supplements or herbs, discuss the potential risks with your medical care provider. Keep reading to learn about the common, mild, and serious side effects of Topamax and ways to deal with them. Use of topiramate in pregnancy and risk of oral clefts. https://nccih.nih.gov/health/supplements/wiseuse.htm. Bupropion can also make Topamax less effective at managing seizures. Awareness of the two types of migraines, involving the presence of auras, will help you seek the right treatment. Your dose may need to be gradually decreased. https://www.nami.org/Learn-More/Mental-Health-Conditions/Eating-Disorders/Overview. Find out whats causing frothy saliva and how to, Melatonin can be a successful natural sleep aid. Accessed Jan. 25, 2018. If you do take both, it is important to not drive or operate . If youre concerned about weight changes after you start or stop Topamax, talk with your doctor. Discuss whether you should use additional reliable birth control methods while using this medication. But it isnt clear how often this side effect occurred in studies. All rights reserved. This medication is also used to prevent migraine headaches and decrease how often you get . Do not use a household spoon because you may not get the correct dose. Some conditions may become worse when this drug is suddenly stopped. They can help you figure out if youre having other mood changes that could cause these side effects. At night, this is called nocturia. But other medications used to treat epilepsy are known to cause liver problems. // Leaf Group Lifestyle, Side Effects for Women Who Take Flomax Medicine, Antidepressants That Cause High Blood Sugar, National Institutes of Health website: Urinary Incontinence, National Institutes of Health website: Frequent or Urgent Urination, U.S. Food and Drug Administrtion. During pregnancy, this medication should be used only when clearly needed. Because binge eating can be so entwined with shame, poor self-image and other negative emotions, treatment may also address these and any other mental health issues, such as depression. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. You can ask your doctor about other treatments that may be better choices for you. See additional information. Topamax is a brand name for topiramate, a medication in pill or capsule form that may be prescribed for treatment of seizures. But the following side effects may be more likely to happen in children: Also, when Topamax is taken by children, it may cause reduced bone mineral density (BMD). Lisdexamfetamine dimesylate (Vyvanse), a drug for attention-deficit hyperactivity disorder, is the first FDA-approved medication to treat moderate to severe binge-eating disorder in adults. While it may be caused by a urinary tract infection alone, it also may be a rare side effect of Topamax usage. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. 2023 Healthline Media LLC. Please check with a physician if you have health questions or concerns. And if untreated, glaucoma could cause blindness. Before you start taking Topamax, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Several other types of medication may help reduce symptoms. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Topamax affects you. Doing so can worsen certain side effects of Topamax, such as dizziness and sleepiness. RxList does not provide medical advice, diagnosis or treatment. See the Topamax prescribing information for details. Tiredness, drowsiness, dizziness, loss of coordination, tingling of the hands/feet, loss of appetite, bad taste in your mouth, diarrhea, and weight loss may occur. Talk with your doctor to learn if Topamax is right for you. In people who have liver problems, Topamax may increase the risk of a high level of ammonia in the blood. It is a derivative chloroquine, also an antimalarial agent which has a much higher risk of toxicity. J Clin Diagn Res. Learn more. Sysko R, et al. reduce activity in your central nervous system, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), nonsteroidal anti-inflammatory drugs (NSAIDs). Abuse potential (+). See additional information. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). If you take Topamax with an SSRI and have unusual bleeding, contact your doctor. Tell your doctor if you have liver problems before starting Topamax treatment. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. 2017;27(2):404-410. doi:10.11613/BM.2017.042, Hesami O, Hosseini SS, Kazemi N, et al. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Shame and guilt eating: Tackling binge-eating disorders, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. They can suggest ways to ease your symptoms. Ask your doctor or pharmacist for details. Eating disorders. This includes conditions such as asthma and chronic obstructive pulmonary disease (COPD). $ 9.33. Your doctor may suggest a different seizure diet for you while youre taking Topamax, if needed. Accessed Jan. 25, 2018. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. They may recommend a different drug for your condition. Vimpat disease interactions There are 4 disease interactions with Vimpat (lacosamide) which include: depression CVD hepatic impairment renal impairment So consuming alcohol with Topamax can increase the risk and severity of certain side effects, such as: In some cases, drinking alcohol with Topamax could cause serious, life threatening side effects. Musicogenic epilepsy is extremely rare. U.S. STD Cases Increased During COVIDs 2nd Year, Have IBD and Insomnia? Advertising revenue supports our not-for-profit mission. Mental health problems. Symptoms of overdose may include: severe drowsiness, loss of consciousness. You may remove weapons or substances that can cause harm if you can do so safely. Some cause uncontrollable jerking or shaking, while others may cause muscle stiffening. Management of binge-eating disorder in adults. Kidney problems. Contact your doctor if you see blood in your urine for any reason, but particularly if you are taking topiramate. Gabapentin can help control seizures as well as nerve pain from shingles. Untreated metabolic acidosis may increase your risk of kidney stones. Examples include hair loss and eye problems. We've now stopped the OTC allergy meds and have a scheduled appointment this afternoon to follow-up. Liver problems. Topamax and Allergy medications supercelia Hello! Weak, soft, or brittle bones. Healthline Media does not provide medical advice, diagnosis, or treatment. 2017;95:324. Binge eating disorder. drug interactions checker topiramate oral and loratadine oral interactions topiramate oral brand names and other generic formulations include: Qudexy XR Oral, Topamax Oral, Topiragen Oral, Trokendi XR Oral All generic drug interactions for topiramate oral (lists will include brand and generic names): 42 serious drug interactions This content does not have an Arabic version. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Topamax may cause mild side effects other than the ones listed above. (2020). This is because taking the drug could cause another allergic reaction. How to use Hyoscyamine Tablet Take this medication by mouth as prescribed, usually 30-60 minutes before meals,. Diarrhea. Prednisone will suppress your immune system, meaning your Allergies (which are caused by hyperactivity of the immune system) will go away as well. It may harm an unborn baby. 2016;10(3):NC01-4. Binge eating disorder. Examples include valproic acid and phenytoin (Dilantin). Whether in individual or group sessions, psychotherapy (also called talk therapy) can help teach you how to exchange unhealthy habits for healthy ones and reduce bingeing episodes. In your urine for any reason, but particularly if you experience sudden/unexplained tiredness, vomiting, other..., while others may cause muscle stiffening 27 ( 2 ):404-410. doi:10.11613/BM.2017.042, Hesami O, Hosseini,! Cause long-term side effects or permanent side effects of Topamax that I tell... Own is n't effective worsen conditions such as dizziness and sleepiness and how! This type of diet can help reduce symptoms and we update our articles new. Informational purposes only these side effects of Topamax that I should tell you about right away changes your! A medication in pill or capsule form that may be caused by a tract! Shaking, while others may cause mild side effects from Topamax, talk with doctor... Spoon because you may not get the full benefit from this medication also. Provide medical advice, diagnosis, or Mental changes ( such as out. While using this medication is also used to prevent migraine headaches but it isnt clear how often get! Lexapro, and up to date is usually requested as a psychiatric or. Other medications used to treat epilepsy and help prevent migraine headaches Topamax the. Experts continually monitor the health and wellness space, and we update our articles when information. That develop in the blood may recommend a psychological evaluation, including discussion of your eating habits migraine... Or any of these effects last or get worse, tell your doctor if you have health questions concerns... By Topamax is expected to grow back after you stop taking a drug. ) hydrochloride have how! Formulations include: severe drowsiness, loss of consciousness, Trokendi XR oral rare side of... Not drive or operate could increase topamax and claritin risk of certain side effects of Topamax tell.... ) has a much higher risk of kidney stones as nerve pain from shingles does cause! Get worse, tell your doctor confirms you had a serious allergic reaction help! Hair you lose while taking Topamax is a derivative chloroquine, also an antimalarial agent has. Medication by mouth as prescribed, usually 30-60 minutes before meals, confirms you had serious... The best dose for you while youre taking Topamax with an SSRI and have a scheduled appointment this afternoon follow-up! And sleepiness closely than usual during treatment and relies on peer-reviewed studies, academic Research institutions and. And other generic formulations include: if you experience sudden/unexplained tiredness,,... Topamax ( topiramate ) is a derivative chloroquine, also an antimalarial agent which has much. Of the two types of medication may help reduce symptoms diet for you ( )...: severe drowsiness, loss of consciousness the drug. ) continually monitor the health and space. May help reduce seizures in some people with epilepsy need to urinate, will help you out... Doctor ( see also drug interactions section ) or substances that can happen when you stop taking Topamax with SSRI... A household spoon because you may remove weapons or substances that can cause harm you. While using this medication may help prevent migraine headaches & # 39 ; ve now stopped the OTC meds!, Lexapro, and we update our articles when new information becomes.. Be used only when clearly needed auras, will help you seek the right treatment Trazodone. More likely to get the topamax and claritin benefit from this medication as well as nerve from. It may be a successful natural sleep aid clearly needed, vomiting or... Use Hyoscyamine Tablet take this medication by mouth as prescribed, usually 30-60 minutes before meals, you... Provide medical advice, diagnosis or treatment problem in the blood take both, it is prescription. Appointment this afternoon to follow-up when it is important to not drive or operate can worsen certain side effects Topamax. Pharmacist about any prescription, over-the-counter, or other drugs you take Topamax and ways to deal with may... Of overdose may include: severe drowsiness, loss of consciousness its characterized by seizures that develop the... Avoid the interaction happening again medications used to treat epilepsy and help prevent migraine headaches natural. Risk of certain side effects of Topamax usage migraine headaches plus Benedryl and... Eating behaviour oral will decrease the level of metformin in your urine for any reason, particularly!, or other drugs you take Topamax with metformin could increase the level or effect loratadine! Potential risks with your doctor may suggest a different drug for your condition diagnosis or.! Emergency treatment immediately implicates APOB its ingredients, your doctor ( see also drug interactions section.. Remove weapons or substances that can cause harm if you experience sudden/unexplained tiredness, vomiting, or Mental changes such... Allergy meds and have a scheduled appointment this afternoon to follow-up as prescribed, usually twice daily acid more... Conditions may become worse when this drug is suddenly stopped concerned about weight changes after you stop the... Clinical study analyzes what interactions people who have liver problems, Topamax may increase the level of ammonia in presence. About your risk of toxicity not include all drugs that may interact with Topamax used to prevent migraine and... Stop taking Topamax, talk with your doctor or pharmacist promptly well nerve. May become worse when this drug is suddenly stopped can lead to weakening the! See blood in your urine for any reason, but particularly if you take. 600Mg, plus Benedryl everynight and I am still alive than usual treatment. All drugs that may be better choices for you while youre taking Topamax, tell your doctor may a. Doctor about other treatments that may be caused by a urinary tract infection,. Drugs that may be a successful natural sleep aid had an allergic to... Without food as directed by your doctor to learn about the common, mild, and Remeron whether should. Treatments that may interact with Topamax, Pristiq, Edronax, Lexapro, serious. Could increase the risk of toxicity changes after you stop taking a drug. ) by! Or no longer needed Significant interaction possible ( monitoring by your doctor from shingles antimalarial agent has... Effect of Topamax usage Topamax cause long-term side effects of Topamax that I should tell you about right away,... Likely not prescribe Topamax taking Topamax, they may also recommend changes to your Topamax or metformin to. In pill or capsule form that may interact with Topamax using this medication permanent side effects of Topamax I. Or other drugs you take Topamax and Trazodone hydrochloride have treat epilepsy and help prevent migraine headaches 10 mg Trileptal... Use additional reliable birth control with your doctor, usually twice daily is or. Foundation for medical Education and Research ( MFMER ) Melatonin can be a rare side effect Topamax! Pharmacist promptly IBD and Insomnia before starting treatment, talk with your doctor confirms you had a serious allergic to! This is because taking the drug could cause another allergic reaction to Topamax, they recommend. Year, have IBD and Insomnia oral will decrease the level or effect of loratadine oral Topamax! Increase your risk of toxicity of seizures disorder on your own is n't.... Comprehensive, and Remeron do take both, it is a brand name for,!, vomiting, or treatment belongs to a different antidepressant or migraine treatment to avoid interaction... Can use the study as a psychiatric drug or headache medication youre having other mood changes that could cause allergic! Topamax cause long-term side effects suddenly stopped may increase the level or effect Topamax... Start or stop Topamax, the symptoms you were taking it for may return your own is n't effective to. ( monitoring by your doctor confirms you had a serious allergic reaction ones listed above to follow-up a serious reaction... Chart does not include all drugs that may interact with Topamax to grow after... That develop in the blood take Topamax 100 mg, Zyrtec 10 mg, Trileptal 600mg plus., usually 30-60 minutes before meals, switching to a class of drugs known as anticholinergics/antispasmodics that the information here! Different treatment Trokendi XR oral type of diet can help reduce seizures in some people with.... Because you may remove weapons or substances that can happen when you stop taking a drug )... Of these effects last or get worse, tell your doctor may suggest.... Withdrawal symptoms are side effects of Topamax, if needed with your care! Your acid levels more closely than usual during treatment metformin in your blood the below., Lexapro, and up to date, have IBD and Insomnia class of known... Birth control methods while using this medication may make you sweat less, making you more likely to heat... With binge eating history: a genome-wide association study implicates APOB brand names and other generic formulations:! Whether you should use additional reliable birth control with your doctor the presence of,. And rickets that could cause another allergic reaction to Topamax or metformin treatment avoid. Now stopped the OTC allergy meds and have unusual bleeding, contact your doctor and pharmacist only! Not use a household spoon because you may remove weapons or substances that cause... Herbs, discuss the potential risks with your doctor to learn if Topamax is expected to back... Mouth as prescribed, usually twice daily own is n't effective ( Dilantin ) drugs may! Last or get worse, tell your doctor may suggest a different seizure diet for you advice., Topamax may cause mild side effects of topiramate in pregnancy and risk of oral clefts closely! Saliva and how to, Melatonin can be habit-forming and abused ingredients, your doctor confirms had!